FSP1 is a glutathione-independent ferroptosis suppressor

Sebastian Doll, Florêncio Porto Freitas, Ron Shah, +29

Nature

Redox SignalingSignal TransductionBiochemistryMedicineNatural Sciences +5

A non-canonical vitamin K cycle is a potent ferroptosis suppressor

Eikan Mishima, Junya Ito, Zijun Wu, +24

Nature

Phase separation of FSP1 promotes ferroptosis

Toshitaka Nakamura, Clara Hipp, André Mourão, +10

Nature

Mapping the Human Platelet Lipidome Reveals Cytosolic Phospholipase A2 as a Regulator of Mitochondrial Bioenergetics during Activation

David A. Slatter, Maceler Aldrovandi, Anne O’Connor, +7

Cell Metabolism

Lipid AnalysisMitochondrial BiologyMultiple Fatty AcidsOxidative StressHuman Metabolism +19

Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation

Stephen Clark, Christopher P. Thomas, Victoria J. Hammond, +6

Proceedings of the National Academy of Sciences

Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation

Mariya Misheva, Konstantinos Kotzamanis, Luke C. Davies, +21

Nature Communications

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis

Sarah N. Lauder, Keith Allen‐Redpath, David A. Slatter, +24

Science Signaling

Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation

Maceler Aldrovandi, Victoria J. Hammond, Helen Podmore, +7

Journal of Lipid Research

Preferential Generation of 15-HETE-PE Induced by IL-13 Regulates Goblet Cell Differentiation in Human Airway Epithelial Cells

Jinming Zhao, Yoshinori Minami, Emily Etling, +8

American Journal of Respiratory Cell and Molecular Biology

Asthma15-Hete-pe InducedInflammatory Lung DiseaseLung InflammationLipid Peroxidation +19

Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies

David A. Slatter, Charles Percy, Keith Allen‐Redpath, +18

JCI Insight

Clot FormationImmunologyPathologyInnate ImmunityCoagulation Factor Deficiencies +17