Developing ANN-Kriging hybrid model based on process parameters for prediction of mean residence time distribution in twin-screw wet granulation

Hamza Y. Ismail, Mehakpreet Singh, Shaza Darwish, +6

Powder Technology

Geotechnical EngineeringEngineeringProcess ParametersMechanical EngineeringTwin-screw Wet Granulation +7

Artificial neural network modelling of continuous wet granulation using a twin-screw extruder

Saeed Shirazian, Manuel Kuhs, Shaza Darwish, +2

International Journal of Pharmaceutics

EngineeringMechanical EngineeringGranular MediumConstitutive ModelingTwin-screw Extruder +5

Crystal Nucleation of Tolbutamide in Solution: Relationship to Solvent, Solute Conformation, and Solution Structure

Jacek Żegliński, Manuel Kuhs, Dikshitkumar Khamar, +3

Chemistry - A European Journal

Crystal StructureCrystal NucleationEngineeringNucleation DifficultyOrganic Chemistry +19

Effect of poly ethylene glycol on the mechanical and thermal properties of bioactive poly(ε-caprolactone) melt extrudates for pharmaceutical applications

Paula Douglas, Ahmad B. Albadarin, M. Sajjia, +4

International Journal of Pharmaceutics

Materials SciencePoly Ethylene GlycolEngineeringPharmaceutical ApplicationsPolymer Technology +7

Probing Crystal Nucleation of Fenoxycarb from Solution through the Effect of Solvent

Jacek Żegliński, Manuel Kuhs, K. Renuka Devi, +4

Crystal Growth & Design

Chemical KineticsMolecular DynamicsCrystal NucleationInduction Time ExperimentsMolecular Thermodynamics +13

Influence of History of Solution in Crystal Nucleation of Fenoxycarb: Kinetics and Mechanisms

Manuel Kuhs, Jacek Żegliński, Åke C. Rasmuson

Crystal Growth & Design

Bioactive PCL matrices with a range of structural & rheological properties

Paula Douglas, Manuel Kuhs, M. Sajjia, +4

Reactive and Functional Polymers

EngineeringPolymer ScienceRheological PropertiesRheological PropertyRheology +4

Amorphous solid dispersions of BCS class II drugs: A rational approach to solvent and polymer selection

Mark T. Davis, David Egan, Manuel Kuhs, +4

Process Safety and Environmental Protection

Thermodynamic Stability Analysis of Tolbutamide Polymorphs and Solubility in Organic Solvents

Michael Svärd, Masood Valavi, Dikshitkumar Khamar, +2

Journal of Pharmaceutical Sciences

Chemical EngineeringEngineeringOrganic SolventsPolymer StabilityTolbutamide Polymorphs +6

Predicting optimal wet granulation parameters for extrusion-spheronisation of pharmaceutical pellets using a mixer torque rheometer

Manuel Kuhs, John C. Moore, Gayathri Kollamaram, +2

International Journal of Pharmaceutics

Rheological MeasurementMixer Torque RheometerEngineeringMechanicsFluid Mechanics +8