Effects of the androgenic growth promoter 17-β-trenbolone on fecundity and reproductive endocrinology of the fathead minnow

Gerald T. Ankley, Kathleen Jensen, Elizabeth A. Makynen, +10

Environmental Toxicology and Chemistry

Mechanistic basis for estrogenic effects in fathead minnow (Pimephales promelas) following exposure to the androgen 17α-methyltestosterone: conversion of 17α-methyltestosterone to 17α-methylestradiol

Michael W. Hornung, Kathleen Jensen, Joseph J. Korte, +5

Aquatic Toxicology

BiologyEndocrine DisruptorsEndocrine MechanismMechanistic BasisPhysiology +8

Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases

Jennifer H. Olker, Joseph J. Korte, Jeffrey S. Denny, +7

Toxicological Sciences

Bioorganic ChemistryChemical BiologyIodothyronine DeiodinasesPharmaceutical ChemistryMedicinal Chemistry +19

Comparison of relative binding affinities of endocrine active compounds to fathead minnow and rainbow trout estrogen receptors

Jeffrey S. Denny, Mark A. Tapper, Patricia K. Schmieder, +4

Environmental Toxicology and Chemistry

Endocrine DisruptorsBiochemistryTwelve ChemicalsMedicineLiver Physiology +11

Screening the ToxCast Phase 1 Chemical Library for Inhibition of Deiodinase Type 1 Activity

Michael W. Hornung, Joseph J. Korte, Jennifer H. Olker, +5

Toxicological Sciences

Bioorganic ChemistryTh DisruptionDeiodinase Type 1Chemical BiologyEnzymatic Modification +18

Temporal Variation in the Estrogenicity of a Sewage Treatment Plant Effluent and Its Biological Significance

Dalma Martinović‐Weigelt, Jeffrey S. Denny, Patricia K. Schmieder, +2

Environmental Science & Technology

Use of Trout Liver Slices To Enhance Mechanistic Interpretation of Estrogen Receptor Binding for Cost-Effective Prioritization of Chemicals within Large Inventories

Patricia K. Schmieder, Mark A. Tapper, Jeffrey S. Denny, +4

Environmental Science & Technology

Female Reproductive FunctionToxicological MechanismLarge InventoriesBioanalysisToxicology +22

In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase

Jennifer H. Olker, Joseph J. Korte, Jeffrey S. Denny, +5

Toxicology in Vitro

Iodotyrosine DeiodinaseBiochemistryNatural SciencesVitro ScreeningBioanalysis +5

Optimization of a precision-cut trout liver tissue slice assay as a screen for vitellogenin induction: comparison of slice incubation techniques

P. Schmieder, Mark A. Tapper, Anne L. Linnum, +3

Aquatic Toxicology

PathogenesisPathologySlice Incubation TechniquesFish ImmunologyVitellogenin Induction +1

A rule-based expert system for chemical prioritization using effects-based chemical categories

P. Schmieder, Richard C. Kolanczyk, Michael W. Hornung, +4

SAR and QSAR in environmental research

Artificial IntelligenceDrug TargetEngineeringChemical AnalysisIndustrial Engineering +26