Landscape of immune microenvironment in hepatocellular carcinoma and its additional impact on histological and molecular classification

Yutaka Kurebayashi, Hidenori Ojima, Hanako Tsujikawa, +7

Hepatology

CD8+ tissue-resident memory T cells promote liver fibrosis resolution by inducing apoptosis of hepatic stellate cells

Yuzo Koda, Toshiaki Teratani, Po–Sung Chu, +11

Nature Communications

OATP1B3 expression is strongly associated with Wnt/β-catenin signalling and represents the transporter of gadoxetic acid in hepatocellular carcinoma

Akihisa Ueno, Yohei Masugi, Ken Yamazaki, +10

Journal of Hepatology

MedicineLiver PhysiologyOatp1b3 ExpressionGadoxetic AcidPathology +7

Upregulation of integrin β4 promotes epithelial–mesenchymal transition and is a novel prognostic marker in pancreatic ductal adenocarcinoma

Yohei Masugi, Ken Yamazaki, Katsura Emoto, +6

Laboratory Investigation

Tumor BiologyPancreatic CancerMedicineEpithelial–mesenchymal TransitionPathology +8

Immunovascular classification of HCC reflects reciprocal interaction between immune and angiogenic tumor microenvironments

Yutaka Kurebayashi, Kosuke Matsuda, Akihisa Ueno, +11

Hepatology

Upregulated SMAD3 promotes epithelial–mesenchymal transition and predicts poor prognosis in pancreatic ductal adenocarcinoma

Ken Yamazaki, Yohei Masugi, Kathryn Effendi, +8

Laboratory Investigation

Tumor BiologyPancreatic CancerMedicineEpithelial–mesenchymal TransitionCancer Cell Biology +8

Quantitative assessment of liver fibrosis reveals a nonlinear association with fibrosis stage in nonalcoholic fatty liver disease

Yohei Masugi, Tokiya Abe, Hanako Tsujikawa, +13

Hepatology Communications

Presence of primary cilia in cancer cells correlates with prognosis of pancreatic ductal adenocarcinoma

Katsura Emoto, Yohei Masugi, Ken Yamazaki, +5

Human Pathology

Tumor BiologyPancreatic CancerMedicinePathologyPancreatic Surgery +6

Immunohistochemical molecular analysis indicates hepatocellular carcinoma subgroups that reflect tumor aggressiveness

Hanako Tsujikawa, Yohei Masugi, Ken Yamazaki, +3

Human Pathology

Immunohistochemical Molecular AnalysisHepatologyHepatocellular Carcinoma SubgroupsHistopathologyPathology +7

Plasmacytoid dendritic cells protect against immune-mediated acute liver injury via IL-35

Yuzo Koda, Nobuhiro Nakamoto, Po–Sung Chu, +15

Journal of Clinical Investigation

ImmunologyPathologyImmunologic MechanismImmunotherapyAutoimmune Liver Disease +17