Concepedia

Author

Chitra M. Vaidya

Harvard University

Also Known As

Chitra M Vaidya, Chitra M. Vaidya, Chitra Vaidya

8

Publications

140

Citations

6

H-Index

11

Concepts

All Affiliations

Harvard UniversityDana-Farber Cancer Institute
CM

About

Chitra M. Vaidya is an author at Harvard University specializing in drug discovery, medicine, and pharmacology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

2

2

49

2

Pharmacology

2

2

49

3

Natural Sciences

1

1

27

4

Biochemistry

1

1

27

5

Bioorganic Chemistry

1

1

27

Chitra M. Vaidya

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5

Publications

104

Citations

5

H-Index

YearCitations

Synthesis and Potent Antifolate Activity and Cytotoxicity of B-Ring Deaza Analogues of the Nonpolyglutamatable Dihydrofolate Reductase Inhibitor <i>N</i><sup>α</sup>-(4-Amino-4-deoxypteroyl)-<i>N</i><sup>δ</sup>-hemiphthaloyl-<scp>l</scp>-ornithine (PT523)

A. Rosowsky, Joel E. Wright, Chitra M. Vaidya,

Journal of Medicinal Chemistry

1998

27

Analogues of the Potent Nonpolyglutamatable Antifolate <i>N</i><sup>α</sup>-(4-Amino-4-deoxypteroyl)-<i>N</i><sup>δ</sup>-hemiphthaloyl-<scp>l</scp>-ornithine (PT523) with Modifications in the Side Chain, <i>p</i>-Aminobenzoyl Moiety, or 9,10-Bridge:  Synthesis and in Vitro Antitumor Activity

A. Rosowsky, Joel E. Wright, Chitra M. Vaidya,

Journal of Medicinal Chemistry

2000

22

Efficient utilization of the reduced folate carrier in CCRF-CEM human leukemic lymphoblasts by the potent antifolate Nα-(4-amino-4-deoxypteroyl)-Nδ-hemiphthaloyl-l-ornithine (PT523) and its B-ring analogues

Joel E. Wright, Chitra M. Vaidya, Yingnan Chen,

Biochemical Pharmacology

2000

22

Analogues of <i>N</i><sup>α</sup>-(4-Amino-4-deoxypteroyl)-<i>N</i><sup>δ</sup>-hemiphthaloyl-<scp>l</scp>-ornithine (PT523) Modified in the Side Chain:  Synthesis and Biological Evaluation

A. Rosowsky, Chitra M. Vaidya, Henry Bader,

Journal of Medicinal Chemistry

1997

20

Synthesis and In Vitro Antitumor Activity of New Deaza Analogues of the Nonpolyglutamatable Antifolate<i>N</i><sup>α</sup>-(4-Amino-4-deoxypteroyl)-<i>N</i><sup>δ</sup>-hemiphthaloyl-<scp>l</scp>-ornithine (PT523)

Chitra M. Vaidya, Joel E. Wright, A. Rosowsky

Journal of Medicinal Chemistry

2002

13

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