Rama F. Pranadinata

TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin

Lee Swanson, Gajanan D. Katkar, Julian S. Tam et al. · Proceedings of the National Academy of Sciences · 2020 · 107 citations · Full text

Life Sciences, Biochemistry, Immunology +15

E-cigarettes compromise the gut barrier and trigger inflammation

Aditi Sharma, Jasper Lee, Ayden G. Fonseca et al. · iScience · 2021 · 82 citations · Full text

Life Sciences, Immunology, Toxicology +17

Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease

Debashis Sahoo, Lee Swanson, Ibrahim M. Sayed et al. · Nature Communications · 2021 · 82 citations · Full text

Life Sciences, Bioinformatics, Systems Biology +17

Overcoming Preclinical Safety Obstacles to Discover (<i>S</i>)-<i>N</i>-((1,2,3,5,6,7-Hexahydro-<i>s</i>-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5<i>H</i>-pyrazolo[5,1-<i>b</i>][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor

Christopher McBride, Lynnie Trzoss, Davide Povero et al. · Journal of Medicinal Chemistry · 2022 · 73 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

ELMO1 Regulates Autophagy Induction and Bacterial Clearance During Enteric Infection

Arup Sarkar, Courtney Tindle, Rama F. Pranadinata et al. · The Journal of Infectious Diseases · 2017 · 43 citations · Full text

Life Sciences, Immunology, Microbiology +17