Timothy G. Lease

The type 2 intramolecular imino Diels-Alder reaction. Synthesis and structural characterization of bicyclo[n.3.1] bridgehead olefin/bridgehead lactams

Timothy G. Lease, Kenneth J. Shea · Journal of the American Chemical Society · 1993 · 84 citations

Structural Characterization, Engineering, Alkene Metathesis +10

Synthesis and x-ray crystal structure of a highly strained anti-Bredt olefin/anti-Bredt lactam. exo-2-Carbomethoxy-1-aza-8-oxobicyclo[3.3.1]non-4-ene

Kenneth J. Shea, Timothy G. Lease, Joseph W. Ziller · Journal of the American Chemical Society · 1990 · 44 citations

Materials Science, X-ray Crystallography, Crystal Structure +15

Solid-Phase Synthesis of 2,4-Diaminoquinazoline Libraries

Jeffrey M. Dener, Timothy G. Lease, Aaron R. Novack et al. · Journal of Combinatorial Chemistry · 2001 · 16 citations

Combinatorial Chemistry, Medicinal Chemistry, Solid-phase Synthesis +11

Integration of optimized substituent patterns to produce highly potent 4-aryl-pyridine glucagon receptor antagonists

Gaétan Ladouceur, James H. Cook, Donald L. Hertzog et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 13 citations · Full text

Medicinal Chemistry, Biochemistry, G Protein-coupled Receptor +10