Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway

Yulin Peng, Yan Wang, Ning Tang, +10

Journal of Experimental & Clinical Cancer Research

Molecular Design Strategy to Construct the Near-Infrared Fluorescent Probe for Selectively Sensing Human Cytochrome P450 2J2

Jing Ning, Tao Liu, Peipei Dong, +13

Journal of the American Chemical Society

Human transporters, <scp>PEPT</scp>1/2, facilitate melatonin transportation into mitochondria of cancer cells: An implication of the therapeutic potential

Xiaokui Huo, Chao Wang, Zhenlong Yu, +9

Journal of Pineal Research

Chemical BiologyCellular PhysiologyTumor BiologyMembrane TransportMitochondrial Membrane +16

Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells

Jian-Jun Lu, Lingyi Fu, Zhipeng Tang, +9

Oncotarget

Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model

Cheng‐Peng Sun, Junjun Zhou, Zhenlong Yu, +5

Proceedings of the National Academy of Sciences

Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury

Juan Zhang, Min Zhang, Xiaokui Huo, +6

ACS Central Science

A genomic compendium of cultivated human gut fungi characterizes the gut mycobiome and its relevance to common diseases

Qiulong Yan, Shenghui Li, Qingsong Yan, +25

Cell

Fungal DiversityGut MycobiomeGut MicrobiologyFungal EvolutionFungal Biology +6

Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells

Zhenlong Yu, Wei Guo, Xiaochi Ma, +15

Molecular Cancer

Targeting PDK1 with dichloroacetophenone to inhibit acute myeloid leukemia (AML) cell growth

Lijun Qin, Yun Tian, Zhenlong Yu, +9

Oncotarget

Melatonin Enhances the Anti-Tumor Effect of Fisetin by Inhibiting COX-2/iNOS and NF-κB/p300 Signaling Pathways

Canhui Yi, Yong Zhang, Zhenlong Yu, +8

PLoS ONE

Chemoprevention StrategyMelanoma TreatmentCell DeathPharmacotherapyMelanoma Cells +16