Yukihiro Tachi

Hypoxia-selective activation of 5-fluorodeoxyuridine prodrug possessing indolequinone structure: radiolytic reduction and cytotoxicity characteristics

Kazuhito Tanabe, Yuji Makimura, Yukihiro Tachi et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 45 citations

5-Fluorodeoxyuridine Prodrug, Hypoxia-selective Activation, Biochemistry +9

In vitro and in vivo evaluation of novel antitumor prodrugs of 5-fluoro-2′-deoxyuridine activated by hypoxic irradiation

Yuta Shibamoto, Yukihiro Tachi, Kazuhito Tanabe et al. · International Journal of Radiation Oncology*Biology*Physics · 2004 · 26 citations · Full text

Medicinal Chemistry, Vivo Evaluation, Medicine +9

One-Electron reduction characteristics of N(3)-Substituted 5-fluorodeoxyuridines synthesized as radiation-Activated prodrugs

Kazuhito Tanabe, Y. Mimasu, Akira Eto et al. · Bioorganic & Medicinal Chemistry · 2003 · 20 citations

Combinatorial Chemistry, One-electron Reduction Characteristics, Organic Chemistry +4

Synthesis and DNA cleavage reaction characteristics of enediyne prodrugs activated via an allylic rearrangement by base or UV irradiation

Yukihiro Tachi, Wei‐Min Dai, Kazuhito Tanabe et al. · Bioorganic & Medicinal Chemistry · 2006 · 16 citations

Allylic Rearrangement, Engineering, Biochemistry +12

Comparison of 5-Fluorouracil and 5-Fluoro-2'-Deoxyuridine as an Effector in Radiation-Activated Prodrugs

Yuta Shibamoto, Y. Mimasu, Yukihiro Tachi et al. · Journal of Chemotherapy · 2002 · 11 citations