Brian W. Simons

Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation

Craig S. Schneider, Qingguo Xu, Nicholas J. Boylan et al. · Science Advances · 2017 · 302 citations · Full text

Nanoparticles, Nanomedicine, Asthma +13

A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors

Daruka Mahadevan, Laurence Cooke, Christopher Riley et al. · Oncogene · 2007 · 277 citations

Imatinib Resistance, Chromatin, Oncology +8

Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition

Ulf D. Kahlert, Donata Maciaczyk, Soroush Doostkam et al. · Cancer Letters · 2012 · 236 citations

Vitro Motility, Epithelial-to-mesenchymal Transition, Developmental Biology +11

Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee

Michael Ittmann, Jiaoti Huang, Enrico Radaelli et al. · Cancer Research · 2013 · 235 citations · Full text

Tumor Biology, Urology, Genitourinary Cancer +15

Targeting the EMT transcription factor TWIST1 overcomes resistance to EGFR inhibitors in EGFR-mutant non-small-cell lung cancer

Zachary A. Yochum, Jessica Cades, Hailun Wang et al. · Oncogene · 2018 · 180 citations · Full text

Systems Biology, Medicine, Egfr Inhibitors +8