Fumihiko Hakuno

Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity

Toshiaki Fukushima, Hidehito Yoshihara, Haruka Furuta et al. · Nature Communications · 2015 · 87 citations · Full text

Insulin-like Growth Factor-I-Dependent Signal Transduction Pathways Leading to the Induction of Cell Growth and Differentiation of Human Neuroblastoma Cell Line SH-SY5Y. The Roles of MAP Kinase Pathway and PI 3-Kinase Pathway.

Shigekazu Kurihara, Fumihiko Hakuno, Shin‐Ichiro Takahashi · Endocrine Journal · 2000 · 81 citations · Full text

Serine Phosphorylation by mTORC1 Promotes IRS-1 Degradation through SCFβ-TRCP E3 Ubiquitin Ligase

Yosuke Yoneyama, Tomomi Inamitsu, Kazuhiro Chida et al. · iScience · 2018 · 78 citations · Full text

KIBRA Suppresses Apical Exocytosis through Inhibition of aPKC Kinase Activity in Epithelial Cells

Yohei Yoshihama, Kazunori Sasaki, Yosuke Horikoshi et al. · Current Biology · 2011 · 75 citations · Full text

Apkc Kinase Activity, Signal Transduction, Molecular Physiology +11

Signalling pathways of insulin-like growth factor-I that are augmented by cAMP in FRTL-5 cells

Miyako Ariga, Taku Nedachi, Masakazu Akahori et al. · Biochemical Journal · 2000 · 64 citations · Full text

Human Growth, Insulin Receptor, Cell Growth +18