Michael S. Regan

Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics

Sonja Bergmann, Sean Lawler, Yuan Qu et al. · Nature Protocols · 2018 · 281 citations

Pharmacy, Neuroscience, Pharmacology +14

Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji et al. · Cancer Discovery · 2023 · 154 citations · Full text

Medicine, Cancer Biology, Oncology +14

A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma

Sharmistha Pal, Jakub Kaplan, Huy Nguyen et al. · Cancer Cell · 2022 · 145 citations · Full text

Medicine, Oncology, Pharmacology +16

De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma

Diana D. Shi, Milan R. Savani, Michael M. Levitt et al. · Cancer Cell · 2022 · 129 citations · Full text

Medicine, Cancer Biology, Oncology +15

Rapid MALDI mass spectrometry imaging for surgical pathology

Sankha S. Basu, Michael S. Regan, Elizabeth C. Randall et al. · npj Precision Oncology · 2019 · 95 citations · Full text

Life Sciences, Pathology, Surgery +17