YAP/TAZ Are Mechanoregulators of TGF-β-Smad Signaling and Renal Fibrogenesis

Stephen G. Szeto, Masahiro Narimatsu, Mingliang Lu, +15

Journal of the American Society of Nephrology

MicroRNA-21 preserves the fibrotic mechanical memory of mesenchymal stem cells

Chen Xi Li, Nilesh P. Talele, Stellar Boo, +6

Nature Materials

MechanobiologyRegenerative MedicineMesenchymal Stem CellsEngineeringMedicine +10

Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation

Franco Klingberg, Melissa L. Chow, Anne B. Koehler, +7

The Journal of Cell Biology

EngineeringMechanotransductionBiomedical EngineeringCellular PhysiologyCell-substrate Interactions +16

Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β

Monika Lodyga, Elizabeth Cambridge, Henna Karvonen, +9

Science Signaling

The fibronectin ED-A domain enhances recruitment of latent TGF-β-binding protein-1 to the fibroblast matrix

Franco Klingberg, Grace Chau, M. Walraven, +9

Journal of Cell Science

Fibroblast MatrixEngineeringLtbp-1 IncorporationCell AdhesionLatent Tgf-β-binding Protein-1 +15

Suppression of the fibrotic encapsulation of silicone implants by inhibiting the mechanical activation of pro-fibrotic TGF-β

Nina Noskovičová, Ronen Schuster, Sander van Putten, +8

Nature Biomedical Engineering

MechanobiologyTissue EngineeringRegenerative MedicineEngineeringBiomaterials +11

YAP1 Is a Driver of Myofibroblast Differentiation in Normal and Diseased Fibroblasts

Bram Piersma, Saskia de Rond, Paul M. N. Werker, +4

American Journal Of Pathology

Myofibroblast DifferentiationFibrosisPathologyFibroblast Growth FactorDisease Gene Identification +4

Discoidin Domain Receptor 1 Mediates Myosin-Dependent Collagen Contraction

Nuno M. Coelho, Pamma D. Arora, Sander van Putten, +5

Cell Reports

Novel micropatterns mechanically control fibrotic reactions at the surface of silicone implants

Hicham Majd, Saja Scherer, Stellar Boo, +8

Biomaterials

Tissue EngineeringMaterials ScienceEngineeringMicrofabricationSilicone Implants +8

Lipocalin-2 induces NLRP3 inflammasome activation via HMGB1 induced TLR4 signaling in heart tissue of mice under pressure overload challenge.

Erfei Song, James W.S. Jahng, Lisa Chong, +15

Queensland's institutional digital repository (The University of Queensland)

MitophagyLung InflammationImmunologyRenal InflammationCell Death +23