Hossein Arefanian

Endoplasmic Reticulum Stress Promotes the Expression of TNF-α in THP-1 Cells by Mechanisms Involving ROS/CHOP/HIF-1α and MAPK/NF-κB Pathways

Nadeem Akhter, Ajit Wilson, Hossein Arefanian et al. · International Journal of Molecular Sciences · 2023 · 90 citations · Full text

ROS/TNF-α Crosstalk Triggers the Expression of IL-8 and MCP-1 in Human Monocytic THP-1 Cells via the NF-κB and ERK1/2 Mediated Signaling

Nadeem Akhter, Ajit Wilson, Reeby Thomas et al. · International Journal of Molecular Sciences · 2021 · 79 citations · Full text

Oxidative Stress Induces Expression of the Toll-Like Receptors (TLRs) 2 and 4 in the Human Peripheral Blood Mononuclear Cells: Implications for Metabolic Inflammation

Nadeem Akhter, Ashraf Al Madhoun, Hossein Arefanian et al. · Cellular Physiology and Biochemistry · 2019 · 73 citations · Full text

Repetitive Intermittent Hyperglycemia Drives the M1 Polarization and Inflammatory Responses in THP-1 Macrophages Through the Mechanism Involving the TLR4-IRF5 Pathway

Fatema Al‐Rashed, Sardar Sindhu, Hossein Arefanian et al. · Cells · 2020 · 57 citations · Full text

Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells

Sulaiman K. Marafie, Eman Alshawaf, Jehad Abubaker et al. · Biological Research · 2019 · 53 citations · Full text