Mesenchymal stem cells enhance growth and metastasis of colon cancer

Kei Shinagawa, Yasuhiko Kitadai, Miwako Tanaka, +6

International Journal of Cancer

Expression of platelet‐derived growth factor (PDGF)‐B and PDGF‐receptor β is associated with lymphatic metastasis in human gastric carcinoma

Michiyo Kodama, Yasuhiko Kitadai, Tomonori Sumida, +7

Cancer Science

Human GrowthPathologyCancer BiologyTumor BiologyPlatelet‐derived Growth Factor +17

Mesenchymal Stem Cells Induce Epithelial to Mesenchymal Transition in Colon Cancer Cells through Direct Cell-to-Cell Contact

Hidehiko Takigawa, Yasuhiko Kitadai, Kei Shinagawa, +5

Neoplasia

Biological MicroenvironmentsPathologyTumor BiologyEpithelial-mesenchymal TransitionColon Cancer Cells +16

Stroma‐directed imatinib therapy impairs the tumor‐promoting effect of bone marrow‐derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer

Kei Shinagawa, Yasuhiko Kitadai, Miwako Tanaka, +8

International Journal of Cancer

Cell TherapyCancer BiologyTumor BiologyImatinib TherapyOncology +19

Crucial involvement of the CCL3‐CCR5 axis‐mediated fibroblast accumulation in colitis‐associated carcinogenesis in mice

Soichiro Sasaki, Tomohisa Baba, Kei Shinagawa, +2

International Journal of Cancer

Anti‐stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model

Tomonori Sumida, Yasuhiko Kitadai, Kei Shinagawa, +7

International Journal of Cancer

Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma

Hidehiko Takigawa, Yasuhiko Kitadai, Kei Shinagawa, +5

Cancer Science

Life-threatening bleeding and acquired factor V deficiency associated with primary systemic amyloidosis

Yasuyuki Emori, Makoto Sakugawa, K Niiya, +10

Blood Coagulation & Fibrinolysis

mTOR and PDGF Pathway Blockade Inhibits Liver Metastasis of Colorectal Cancer by Modulating the Tumor Microenvironment

Ryo Yuge, Yasuhiko Kitadai, Kei Shinagawa, +4

American Journal Of Pathology

MedicineColorectal CancerPathologyCancer BiologyOncology +4

Combining Molecular Targeted Drugs to Inhibit Both Cancer Cells and Activated Stromal Cells in Gastric Cancer

Mieko Onoyama, Yasuhiko Kitadai, Yuichiro Tanaka, +5

Neoplasia