Serge Turcaud

Mixed-inhibitor-prodrug as a new approach toward systemically active inhibitors of enkephalin-degrading enzymes

Marie Claude Fournié-Zaluski, Pascale Coric, Serge Turcaud et al. · Journal of Medicinal Chemistry · 1992 · 140 citations

Pharmaceutical Science, Pharmacotherapy, Enkephalin-degrading Enzymes +18

Antidepressant-type effects of endogenous enkephalins protected by systemic RB 101 are mediated by opioid δ and dopamine D1 receptor stimulation

Ana Baamonde, Valérie Daugé, Mariano Ruiz‐Gayo et al. · European Journal of Pharmacology · 1992 · 125 citations

Psychoactive Drug, Psychiatry, Opioid δ +10

Inhibition of the enkephalin-metabolizing enzymes by the first systemically active mixed inhibitor prodrug RB 101 induces potent analgesic responses in mice and rats.

Florence Noble, Jean-Marc Soleilhac, Evelyne Soroca-Lucas et al. · Journal of Pharmacology and Experimental Therapeutics · 1992 · 116 citations

Potent and systemically active aminopeptidase N inhibitors designed from active-site investigation

Marie Claude Fournié-Zaluski, Pascale Coric, Serge Turcaud et al. · Journal of Medicinal Chemistry · 1992 · 88 citations · Full text

Hot Plate Test, Medicinal Chemistry, Amino Acids +14

New Dual Inhibitors of Neutral Endopeptidase and Angiotensin-Converting Enzyme: Rational Design, Bioavailability, and Pharmacological Responses in Experimental Hypertension

Marie‐Claude Fournié‐Zaluski, Pascale Coric, Serge Turcaud et al. · Journal of Medicinal Chemistry · 1994 · 79 citations · Full text

Hypertension, Bioorganic Chemistry, Cardiovascular Pharmacology +19