Damien Abreu

Dominant ER Stress–Inducing <i>WFS1</i> Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts

Elisa De Franco, Sarah E. Flanagan, Takuya Yagi et al. · Diabetes · 2017 · 109 citations

Medicine, Genetics, Molecular Genetics +17

Primary cilia control glucose homeostasis via islet paracrine interactions

Jing W. Hughes, Jung Hoon Cho, Hannah Conway et al. · Proceedings of the National Academy of Sciences · 2020 · 100 citations · Full text

Life Sciences, Endocrinology, Physiology +17

Calpain inhibitor and ibudilast rescue β cell functions in a cellular model of Wolfram syndrome

Lien D. Nguyen, Tom T. Fischer, Damien Abreu et al. · Proceedings of the National Academy of Sciences · 2020 · 49 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Wolfram syndrome 1 gene regulates pathways maintaining beta-cell health and survival

Damien Abreu, Rie Asada, John M.P. Revilla et al. · Laboratory Investigation · 2020 · 45 citations · Full text

Life Sciences, Genetics, Molecular Biology +9

A phase Ib/IIa clinical trial of dantrolene sodium in patients with Wolfram syndrome

Damien Abreu, Stephen Stone, Toni S. Pearson et al. · JCI Insight · 2021 · 39 citations · Full text

Medicine, Neurology, Pharmacotherapy +12