The Genetic Landscape of a Cell

Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, +50

Science

Coherent SubsetsGeneticsMolecular BiologyMolecular GeneticsGenomics +22

Cell Cycle Regulated Transport Controlled by Alterations in the Nuclear Pore Complex

Taras Makhnevych, C. Patrick Lusk, Andrea M. Anderson, +2

Cell

Signal TransductionOrganelle DynamicIntracellular TransportMembrane TransportMolecular Biology +5

Global Map of SUMO Function Revealed by Protein-Protein Interaction and Genetic Networks

Taras Makhnevych, Yaroslav Sydorskyy, Xiaofeng Xin, +8

Molecular Cell

Functional GenomicsInteractomicsMedicineGeneticsNatural Sciences +13

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

Franco J. Vizeacoumar, Roland Arnold, Frederick S. Vizeacoumar, +29

Molecular Systems Biology

Karyopherins in nuclear pore biogenesis

C. Patrick Lusk, Taras Makhnevych, Marcello Marelli, +2

The Journal of Cell Biology

The role of karyopherins in the regulated sumoylation of septins

Taras Makhnevych, Christopher P. Ptak, C. Patrick Lusk, +2

The Journal of Cell Biology

Lumenal interactions in nuclear pore complex assembly and stability

William T. Yewdell, Paolo Colombi, Taras Makhnevych, +1

Molecular Biology of the Cell

ChromatinPore StructureBiochemistryMedicineNatural Sciences +13

Nutritional status modulates box C/D snoRNP biogenesis by regulated subcellular relocalization of the R2TP complex

Yoshito Kakihara, Taras Makhnevych, Liang Zhao, +2

Genome biology

Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10

Wei Zhang, Maria A. Sartori, Taras Makhnevych, +13

Journal of Molecular Biology

MedicineProteomicsPharmacologyCell BiologyDrug Discovery

The TFIIH Subunit Tfb3 Regulates Cullin Neddylation

Gwénaël Rabut, Gaëlle Le Dez, Rati Verma, +6

Molecular Cell

Transcriptional RegulationSignal TransductionMolecular RegulationCellular Regulatory MechanismMedicine +2