Sachin Bhagwat

Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β-Lactamase Inhibitors and β-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234

Krisztina M. Papp‐Wallace, Nhu Q. Nguyen, Michael R. Jacobs et al. · Journal of Medicinal Chemistry · 2018 · 150 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

WCK 5107 (Zidebactam) and WCK 5153 Are Novel Inhibitors of PBP2 Showing Potent “β-Lactam Enhancer” Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones

Bartolomé Moyá, Isabel M. Barceló, Sachin Bhagwat et al. · Antimicrobial Agents and Chemotherapy · 2017 · 131 citations

Life Sciences, Microbiology, Pharmacology +17

Potent β-Lactam Enhancer Activity of Zidebactam and WCK 5153 against Acinetobacter baumannii, Including Carbapenemase-Producing Clinical Isolates

Bartolomé Moyá, Isabel M. Barceló, Sachin Bhagwat et al. · Antimicrobial Agents and Chemotherapy · 2017 · 76 citations · Full text

Life Sciences, Pharmacology, Antimicrobial Pharmacology +16

Substituted 3-((Z)-2-(4-nitrophenyl)-2-(1H-tetrazol-5-yl) vinyl)-4H-chromen-4-ones as novel anti-MRSA agents: Synthesis, SAR, and in-vitro assessment

Santosh D. Diwakar, Sachin Bhagwat, Murlidhar S. Shingare et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 66 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

High prevalence of Escherichia coli clinical isolates in India harbouring four amino acid inserts in PBP3 adversely impacting activity of aztreonam/avibactam

Hariharan Periasamy, Prashant Joshi, Snehal Palwe et al. · Journal of Antimicrobial Chemotherapy · 2020 · 64 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +12