Lena J. McLaughlin

DNA methyltransferase inhibitors induce a BRCAness phenotype that sensitizes NSCLC to PARP inhibitor and ionizing radiation

Rachel Abbotts, Michael J. Topper, Christopher Biondi et al. · Proceedings of the National Academy of Sciences · 2019 · 103 citations · Full text

Medicine, Cancer Biology, Oncology +17

Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiency

Lena J. McLaughlin, Lora Stojanovic, Aksinija A. Kogan et al. · Proceedings of the National Academy of Sciences · 2020 · 39 citations · Full text

Life Sciences, Cancer Biology, Molecular Genetics +11

¹⁸F-Fluoromisonidazole Quantification of Hypoxia in Human Cancer Patients Using Image-Derived Blood Surrogate Tissue Reference Regions

Mark Muzi, Lanell M. Peterson, Janet OʼSullivan et al. · Journal of Nuclear Medicine · 2015 · 36 citations · Full text

Medicine, Nuclear Medicine, Oncology +17

Activating STING1-dependent immune signaling in <i>TP53</i> mutant and wild-type acute myeloid leukemia

Aksinija A. Kogan, Michael J. Topper, Anna J. Dellomo et al. · Proceedings of the National Academy of Sciences · 2022 · 22 citations · Full text

Life Sciences, Genetics, Oncology +17

The role of nucleoside/nucleotide transport and metabolism in the uptake and retention of 3′-fluoro-3′-deoxythymidine in human B-lymphoblast cells

David Plotnik, Lena J. McLaughlin, Jenny Chan et al. · Nuclear Medicine and Biology · 2011 · 20 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10