Concepedia

Fiona Semple

FS

Statistics

Publications

6

Citations

497

H-Index

6

Active since

2010

Affiliations

Institute of Genetics and Cancer(Current)

University of Edinburgh

Centre for Inflammation Research

Western General Hospital

University of California, Santa Cruz

Fiona Semple is an author at Institute of Genetics and Cancer specializing in medicine, cell biology, and inflammation.

Top concepts

MedicineCell BiologyImmunologyInflammationImmune SystemInnate ImmunityImmune RegulationHost Immune ResponseMolecular ImmunologyImmune Function

Publications per year

2010–2020

6

Publications

6

Human β‐defensin 3 has immunosuppressive activity <i>in vitro</i> and <i>in vivo</i>

Fiona Semple, Sheila Webb, Hsin‐Ni Li et al. · European Journal of Immunology · 2010 · 172 citations · Full text

Human β‐defensin 3 affects the activity of pro‐inflammatory pathways associated with MyD88 and TRIF

Fiona Semple, Heather MacPherson, Sheila Webb et al. · European Journal of Immunology · 2011 · 137 citations · Full text

Innate Immune System, Immunology, Immune Regulation +25

Partial Deletion of Chromosome 8 β-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice

Yu Shan Zhou, Sheila Webb, Laura A. Lettice et al. · PLoS Genetics · 2013 · 100 citations · Full text

Spermatogenesis, Fertility, Genetics +22

Human β‐defensin 3 increases the TLR9‐dependent response to bacterial DNA

Sarah McGlasson, Fiona Semple, Heather MacPherson et al. · European Journal of Immunology · 2017 · 40 citations · Full text

Tlr9-dependent Response, Microbial Pathogens, Adaptive Immune System +23

Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid

Fiona Semple, Heather MacPherson, Sheila Webb et al. · PLoS Genetics · 2015 · 33 citations · Full text

Innate Immune System, Immunology, Immune Regulation +24

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