Gianfranco Distefano

Polycystin-1 Regulates Extracellular Signal-Regulated Kinase-Dependent Phosphorylation of Tuberin To Control Cell Size through mTOR and Its Downstream Effectors S6K and 4EBP1

Gianfranco Distefano, Manila Boca, Isaline Rowe et al. · Molecular and Cellular Biology · 2009 · 193 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Dissection of metabolic reprogramming in polycystic kidney disease reveals coordinated rewiring of bioenergetic pathways

Christine Podrini, Isaline Rowe, Roberto Pagliarini et al. · Communications Biology · 2018 · 107 citations · Full text

Life Sciences, Biochemistry, Molecular Genetics +17

Polycystin-1 Induces Cell Migration by Regulating Phosphatidylinositol 3-kinase-dependent Cytoskeletal Rearrangements and GSK3β-dependent Cell–Cell Mechanical Adhesion

Manila Boca, Lisa D’Amato, Gianfranco Distefano et al. · Molecular Biology of the Cell · 2007 · 101 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

A new Chinese hamster ovary cell line expressing α2,6-sialyltransferase used as universal host for the production of human-like sialylated recombinant glycoproteins

Alessandra Bragonzi, Gianfranco Distefano, Lorraine D. Buckberry et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2000 · 93 citations

Life Sciences, Biochemistry, Molecular Biology +14

Polycystin-1 Induces Resistance to Apoptosis through the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway

Manila Boca, Gianfranco Distefano, Feng Qian et al. · Journal of the American Society of Nephrology · 2006 · 87 citations · Full text

Life Sciences, Cell Biology, Nephrology +17