Marianne Kjalke

High‐dose factor VIIa increases initial thrombin generation and mediates faster platelet activation in thrombocytopenia‐like conditions in a cell‐based model system

Marianne Kjalke, Mirella Ezban, Dougald M. Monroe et al. · British Journal of Haematology · 2001 · 139 citations

Medicine, Hematology, Pharmacology +17

Incorporation of an Active Site Inhibitor in Factor VIIa Alters the Affinity for Tissue Factor

Brit B. Sørensen, Egon Persson, Per‐Ola Freskgård et al. · Journal of Biological Chemistry · 1997 · 133 citations · Full text

Medicine, Molecular Biology, Pharmacology +15

Localization of the disulfide bonds in the NH2-terminal domain of the cellular receptor for human urokinase-type plasminogen activator. A domain structure belonging to a novel superfamily of glycolipid-anchored membrane proteins

Michael Ploug, Marianne Kjalke, Ebbe Rønne et al. · Journal of Biological Chemistry · 1993 · 128 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Rational design of coagulation factor VIIa variants with substantially increased intrinsic activity

Egon Persson, Marianne Kjalke, Ole H. Olsen · Proceedings of the National Academy of Sciences · 2001 · 117 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models

Henning R. Stennicke, Marianne Kjalke, Ditte M. Karpf et al. · Blood · 2013 · 115 citations · Full text

Medicine, Hematology, Pharmacology +2