Anne C. Loweth

Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1beta and Fas ligation.

Anne C. Loweth, Gwyn T. Williams, R. F. L. James et al. · Diabetes · 1998 · 142 citations

Life Sciences, Cell Biology, Endocrinology +17

Evidence for the involvement of cGMP and protein kinase G in nitric oxide‐induced apoptosis in the pancreatic B‐cell line, HIT‐T15

Anne C. Loweth, Gwyn T. Williams, J. H. B. Scarpello et al. · FEBS Letters · 1997 · 105 citations · Full text

Life Sciences, Cell Biology, Pharmacology +16

Islet glutamic acid decarboxylase modified by reactive oxygen species is recognized by antibodies from patients with type 1 diabetes mellitus

Susan Trigwell, Paul Radford, Sean Page et al. · Clinical & Experimental Immunology · 2001 · 72 citations · Full text

Life Sciences, Endocrinology, Immunology +15

Superoxide, nitric oxide, peroxynitrite and cytokine combinations all cause functional impairment and morphological changes in rat islets of Langerhans and insulin secreting cell lines, but dictate cell death by different mechanisms

M. A. Di Matteo, Anne C. Loweth, Steven Thomas et al. · APOPTOSIS · 1997 · 54 citations

Veterinary Medicine, Endocrinology, Physiology +17

Stimulation of insulin secretion by imidazoline compounds is not due to interaction with non‐adrenoceptor idazoxan binding sites

Colin A. Brown, Anne C. Loweth, Stephen A. Smith et al. · British Journal of Pharmacology · 1993 · 45 citations · Full text

Medicine, Biochemistry, Pharmacology +14