Mosun Ayan‐Oshodi

Duloxetine is both an inhibitor and a substrate of cytochrome P4502D6 in healthy volunteers

Michael Skinner, Han‐Yi Kuan, Alan X. Pan et al. · Clinical Pharmacology & Therapeutics · 2003 · 193 citations

Medicine, Pharmacokinetics, Pharmacology +17

Disposition and Metabolism of Semagacestat, a γ-Secretase Inhibitor, in Humans

Ping Yi, Chad E. Hadden, Palaniappan Kulanthaivel et al. · Drug Metabolism and Disposition · 2010 · 22 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

Development Review of the BACE1 Inhibitor Lanabecestat (AZD3293/LY3314814).

John R. Sims, Katherine J. Selzler, AnnCatherine M. Downing et al. · PubMed · 2017 · 22 citations

Medicine, Neurology, Pharmacology +17

Relative Contributions of Presystemic and Systemic Peptidases to Oral Exposure of a Novel Metabotropic Glutamate 2/3 Receptor Agonist (LY404039) After Oral Administration of Prodrug Pomaglumetad Methionil (LY2140023)

William F. Annes, Amanda Long, Jennifer Witcher et al. · Journal of Pharmaceutical Sciences · 2014 · 20 citations

Medicine, Pharmacokinetics, Pharmacology +15

Effects of a novel mGlu2/3 receptor agonist prodrug, LY2140023 monohydrate, on central monoamine turnover as determined in human and rat cerebrospinal fluid

Stephen L. Lowe, Robert A. Dean, Bradley L. Ackermann et al. · Psychopharmacology · 2011 · 17 citations

Life Sciences, Neuroscience, Pharmacology +14