Alexandra E. Stacy

Zinc(II)–Thiosemicarbazone Complexes Are Localized to the Lysosomal Compartment Where They Transmetallate with Copper Ions to Induce Cytotoxicity

Alexandra E. Stacy, Duraippandi Palanimuthu, Paul V. Bernhardt et al. · Journal of Medicinal Chemistry · 2016 · 177 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Di-2-pyridylketone 4,4-Dimethyl-3-thiosemicarbazone (Dp44mT) Overcomes Multidrug Resistance by a Novel Mechanism Involving the Hijacking of Lysosomal P-Glycoprotein (Pgp)

Patric J. Jansson, Tetsuo Yamagishi, Akanksha Arvind et al. · Journal of Biological Chemistry · 2015 · 128 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +15

Structure–Activity Relationships of Di-2-pyridylketone, 2-Benzoylpyridine, and 2-Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug Resistance

Alexandra E. Stacy, Duraippandi Palanimuthu, Paul V. Bernhardt et al. · Journal of Medicinal Chemistry · 2016 · 108 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Evaluation of a Pilot Vancomycin Precision Dosing Advisory Service on Target Exposure Attainment Using an Interrupted Time Series Analysis

Sophie L. Stocker, Jane E. Carland, Stephanie E. Reuter et al. · Clinical Pharmacology & Therapeutics · 2020 · 23 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +15