A non-conserved amino acid variant regulates differential signalling between human and mouse CD28

Nicla Porciello, Paola Grazioli, Antonio Francesco Campese, +11

Nature Communications

The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration

Marta Mastrogiovanni, Pablo Vargas, Thierry Rose, +12

Science Advances

T-regulatory CellImmunologyPathologyAdenomatous Polyposis ColiTumor Biology +15

Atypical CXCL12 signaling enhances neutrophil migration by modulating nuclear deformability

Bianca Calì, Mathieu Deygas, Fabio Munari, +13

Science Signaling

CD28 Individual Signaling Up-regulates Human IL-17A Expression by Promoting the Recruitment of RelA/NF-κB and STAT3 Transcription Factors on the Proximal Promoter

Martina Kunkl, Marta Mastrogiovanni, Nicla Porciello, +4

Frontiers in Immunology

T-regulatory CellImmune RegulationImmunologyImmunologic MechanismIl-17a Gene Expression +17

ISA-2011B, a Phosphatidylinositol 4-Phosphate 5-Kinase α Inhibitor, Impairs CD28-Dependent Costimulatory and Pro-inflammatory Signals in Human T Lymphocytes

Martina Kunkl, Nicla Porciello, Marta Mastrogiovanni, +7

Frontiers in Immunology

Adenomatous Polyposis Coli Modulates Actin and Microtubule Cytoskeleton at the Immunological Synapse to Tune CTL Functions

Marie Juzans, Céline Cuche, Thierry Rose, +4

ImmunoHorizons

Cancer-on-a-chip model shows that the adenomatous polyposis coli mutation impairs T cell engagement and killing of cancer spheroids

Valentin Bonnet, Erik Maikranz, Marianne Madec, +6

Proceedings of the National Academy of Sciences

ImmunologyImmunoeditingCancer SpheroidsImmunotherapyCancer Biology +15

Inflammation in Development and Aging: Insights from the Zebrafish Model

Marta Mastrogiovanni, Francisco J. Martínez‐Navarro, Teresa V. Bowman, +1

International Journal of Molecular Sciences

T cell migration and effector function differences in familial adenomatous polyposis patients with APC gene mutations

Céline Cuche, Marta Mastrogiovanni, Marie Juzans, +20

Frontiers in Immunology