Annette Aichem

Genetic CD21 deficiency is associated with hypogammaglobulinemia

Jens Thiel, Lucas Kimmig, Ulrich Salzer et al. · Journal of Allergy and Clinical Immunology · 2011 · 197 citations

Genetic Disorder, Genetics, Hematology +6

USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis

Annette Aichem, Christiane Pelzer, Sebastian Łukasiak et al. · Nature Communications · 2010 · 92 citations · Full text

Protein Chemistry, Protein Function, Biochemistry +6

The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation

Annette Aichem, Birte Kalveram, Valentina Spinnenhirn et al. · Journal of Cell Science · 2012 · 86 citations · Full text

Immunology, Molecular Biology, Cell Death +26

FAT10 and NUB1L bind to the VWA domain of Rpn10 and Rpn1 to enable proteasome-mediated proteolysis

Neha Rani, Annette Aichem, Gunter Schmidtke et al. · Nature Communications · 2012 · 81 citations · Full text

Proteomic Technology, Protein Function, Biochemistry +13

The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells

Almut Dufner, Agnes Kisser, Sandra Niendorf et al. · Nature Immunology · 2015 · 68 citations

Ubiquitin-specific Protease Usp8, Protein Function, Cell Regulation +11