Andreas Kling

Discovery and Optimization of a Novel Class of Orally Active Nonpeptidic Endothelin-A Receptor Antagonists

Hartmut Riechers, Hans-Peter Albrecht, Willi Amberg et al. · Journal of Medicinal Chemistry · 1996 · 119 citations · Full text

Medicinal Chemistry, Biochemistry, Functional Selectivity +14

Calpain Inhibitor A-705253 Mitigates Alzheimer's Disease–Like Pathology and Cognitive Decline in Aged 3xTgAD Mice

Rodrigo Medeiros, Masashi Kitazawa, Meredith A. Chabrier et al. · American Journal Of Pathology · 2012 · 89 citations

Aged 3Xtgad, Neurodegenerative Diseases, Cognitive Decline +15

Design and synthesis of 1,5- and 2,5-substituted tetrahydrobenzazepinones as novel potent and selective integrin αVβ3 antagonists

Andreas Kling, Gisela Backfisch, Jürgen Delzer et al. · Bioorganic & Medicinal Chemistry · 2003 · 43 citations

Discovery of Novel and Highly Selective Inhibitors of Calpain for the Treatment of Alzheimer’s Disease: 2-(3-Phenyl-1<i>H</i>-pyrazol-1-yl)-nicotinamides

Andreas Kling, Katja Jantos, Helmut Mack et al. · Journal of Medicinal Chemistry · 2017 · 34 citations · Full text

Neurochemical Biomarkers, Pharmacotherapy, Pharmaceutical Chemistry +20

Solution structure of a synthetic N-glycosylated cyclic hexapeptide determined by NMR spectroscopy and MD calculations

Horst Kessler, Hans Matter, Gerd Gemmecker et al. · Journal of the American Chemical Society · 1991 · 34 citations

Nmr Spectroscopy, Chemical Analysis, Glycobiology +17