Junfan Guo

A DddA ortholog-based and transactivator-assisted nuclear and mitochondrial cytosine base editors with expanded target compatibility

Junfan Guo, Wenxia Yu, Min Li et al. · Molecular Cell · 2023 · 45 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

Engineering of near-PAMless adenine base editor with enhanced editing activity and reduced off-target

Xiaofang Cao, Junfan Guo, Shisheng Huang et al. · Molecular Therapy — Nucleic Acids · 2022 · 26 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15

Functional Phosphoproteomics in Cancer Chemoresistance Using CRISPR‐Mediated Base Editors

Jianan Li, Jianxiang Lin, Shisheng Huang et al. · Advanced Science · 2022 · 18 citations · Full text

Medicine, Oncology, Pharmacology +17

CABE-RY: A PAM-flexible dual-mutation base editor for reliable modeling of multi-nucleotide variants

Wanyu Tao, Qing Liu, Shisheng Huang et al. · Molecular Therapy — Nucleic Acids · 2021 · 12 citations · Full text

Life Sciences, Genetics, Molecular Biology +13