Roberta Lugano

Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing

Yuan Xie, Liqun He, Roberta Lugano et al. · JCI Insight · 2021 · 155 citations · Full text

Key Molecular Alterations, Endothelial Cells, High-grade Gliomas +18

CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis

Roberta Lugano, Kalyani Vemuri, Di Yu et al. · Journal of Clinical Investigation · 2018 · 144 citations · Full text

Vessel Maturation, Immunology, Glioma +19

Blockade of the CD93 pathway normalizes tumor vasculature to facilitate drug delivery and immunotherapy

Yi Sun, Wei Chen, Robert J. Torphy et al. · Science Translational Medicine · 2021 · 141 citations · Full text

Immunology, Immunotherapy, Tumor Biology +16

Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Mohanraj Ramachandran, Alessandra Vaccaro, Tiarne van de Walle et al. · Cancer Cell · 2023 · 115 citations · Full text

Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Elise Langenkamp, Lei Zhang, Roberta Lugano et al. · Cancer Research · 2015 · 92 citations

Tumor Innervation, Endothelial Cells, Immunology +18