Sabine Pilari

Lumping of physiologically-based pharmacokinetic models and a mechanistic derivation of classical compartmental models

Sabine Pilari, Wilhelm Huisinga · Journal of Pharmacokinetics and Pharmacodynamics · 2010 · 65 citations

Mechanistic Derivation, Pharmacokinetic Modeling, Pharmacodynamics +12

Monoclonal antibody disposition: a simplified PBPK model and its implications for the derivation and interpretation of classical compartment models

Ludivine Fronton, Sabine Pilari, Wilhelm Huisinga · Journal of Pharmacokinetics and Pharmacodynamics · 2014 · 40 citations

Classical Compartment Models, Systems Biology, Monoclonal Antibody Disposition +10

Modeling Interindividual Variability in Physiologically Based Pharmacokinetics and Its Link to Mechanistic Covariate Modeling

Wilhelm Huisinga, Alexander Solms, Ludivine Fronton et al. · CPT Pharmacometrics & Systems Pharmacology · 2012 · 36 citations · Full text

Physical Activity, Anthropometric Indicator, Physiologically-based Pharmacokinetic Modeling +22

BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models

Ulrike Rauh, Wei Guo, Michael H. Serrano‐Wu et al. · Nature Cancer · 2024 · 23 citations · Full text

Development of Physiologically Based Organ Models to Evaluate the Pharmacokinetics of Drugs in the Testes and the Thyroid Gland

Sabine Pilari, Thomas Gaub, Michael S. Block et al. · CPT Pharmacometrics & Systems Pharmacology · 2017 · 16 citations · Full text

Organ Models, Thyroid Gland, Experimental Pharmacology +18