CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome

Francesca Mari, Sara Azimonti, Ilaria Bertani, +16

Human Molecular Genetics

Early-onset Seizure VariantRett SyndromeGeneticsDisease Gene IdentificationCdkl5 Gene +16

<scp>ASPM</scp> and <scp>CITK</scp> regulate spindle orientation by affecting the dynamics of astral microtubules

Marta Gai, F. Bianchi, Cristiana Vagnoni, +12

EMBO Reports

Astral MicrotubulesSpindle OrientationBiophysical ModelingCell DivisionMolecular Biology +6

Methyl‐CpG‐binding protein 2 is phosphorylated by homeodomain‐interacting protein kinase 2 and contributes to apoptosis

Giorgia Bracaglia, Barbara Conca, Anna Bergo, +6

EMBO Reports

Signal TransductionSignaling PathwayMolecular PathwayMedicineNatural Sciences +10

<i>MECP2</i> mutations affect ciliogenesis: a novel perspective for Rett syndrome and related disorders

Angelisa Frasca, Eleonora Spiombi, Michela Palmieri, +8

EMBO Molecular Medicine

CDKL5 localizes at the centrosome and midbody and is required for faithful cell division

Isabella Barbiero, Davide Valente, Chetan Chandola, +9

Scientific Reports

Spatio-temporal Dynamics and Localization of MeCP2 and Pathological Mutants in Living Cells

Matilde Marchi, Alessia Guarda, Anna Bergo, +4

Epigenetics

Methyl-CpG Binding Protein 2 (MeCP2) Localizes at the Centrosome and Is Required for Proper Mitotic Spindle Organization

Anna Bergo, Marta Strollo, Marta Gai, +7

Journal of Biological Chemistry

Microtubule NucleationProtein AssemblyMolecular BiologyCytoskeletonMendelian Disorder +22

A Novel Mecp2Y120D Knock-in Model Displays Similar Behavioral Traits But Distinct Molecular Features Compared to the Mecp2-Null Mouse Implying Precision Medicine for the Treatment of Rett Syndrome

Anna Gandaglia, Elena Brivio, Sara Carli, +16

Molecular Neurobiology

Knockout MouseMolecular NeuroscienceGenetic DisorderRett SyndromeNeuroscience +3

A Novel Protein, Xenopus p20, Influences the Stability of MeCP2 through Direct Interaction

Maria Stella Carro, Anna Bergo, Mauro Mengoni, +4

Journal of Biological Chemistry