Peter J. Worland

Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells.

Bradley A. Carlson, M M Dubay, Edward A. Sausville et al. · PubMed · 1996 · 537 citations

Medicine, Oncology, Pharmacology +14

Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

Walter Filgueira de Azevedo, H J Mueller-Dieckmann, Ursula Schulze‐Gahmen et al. · Proceedings of the National Academy of Sciences · 1996 · 500 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

UCN-01: a Potent Abrogator of G2 Checkpoint Function in Cancer Cells With Disrupted p53

Qizhi Wang, Songqing Fan, Alan Eastman et al. · JNCI Journal of the National Cancer Institute · 1996 · 447 citations · Full text

Life Sciences, Cell Biology, Oncology +17

The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinomas.

P. Tan, Blake Cady, Molly Wanner et al. · PubMed · 1997 · 354 citations

Medicine, Cancer Biology, Oncology +15

Growth Inhibition With Reversible Cell Cycle Arrest of Carcinoma Cells by Flavone L86-8275

Gurmeet Kaur, M Stetler-Stevenson, S Sebers et al. · JNCI Journal of the National Cancer Institute · 1992 · 351 citations

Medicine, Oncology, Pharmacology +13