Obinna C. Ubah

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development

John Steven, Mischa Müller, Miguel F. Carvalho et al. · Frontiers in Immunology · 2017 · 44 citations · Full text

Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development

Obinna C. Ubah, John Steven, Marina Kovaleva et al. · Frontiers in Immunology · 2017 · 35 citations · Full text

Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography

Obinna C. Ubah, Eric W. Lake, Gihan S. Gunaratne et al. · Nature Communications · 2021 · 35 citations · Full text

X-ray Crystallography, Virus Structure, Viral Evolution +13

An Anti-hTNF-α Variable New Antigen Receptor Format Demonstrates Superior in vivo Preclinical Efficacy to Humira® in a Transgenic Mouse Autoimmune Polyarthritis Disease Model

Obinna C. Ubah, John Steven, A.J. Porter et al. · Frontiers in Immunology · 2019 · 25 citations · Full text

<i>In Vitro</i> ELISA and Cell‐Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA: An Encouraging Milestone to Further Clinical Drug Development

Obinna C. Ubah, A.J. Porter, Caroline J. Barelle · Journal of Immunology Research · 2020 · 16 citations · Full text