Isoneocryptolepine, a Synthetic Indoloquinoline Alkaloid, as an Antiplasmodial Lead Compound

Sabine Van Miert, Steven Hostyn, Bert U. W. Maes, +8

Journal of Natural Products

Antiparasitic AgentPharmacotherapyPharmaceutical ChemistryDrug ResistanceMedicinal Chemistry +15

Synthesis of α‐Carbolines Starting from 2,3‐Dichloropyridines and Substituted Anilines

Steven Hostyn, Gitte Van Baelen, Guy L. F. Lemière, +1

Advanced Synthesis & Catalysis

Po 4Diversity Oriented SynthesisCross-coupling ReactionDerivativesEngineering +9

Synthesis of the benzo-β-carboline isoneocryptolepine: the missing indoloquinoline isomer in the alkaloid series cryptolepine, neocryptolepine and isocryptolepine

Steven Hostyn, Bert U. W. Maes, Luc Pieters, +4

Tetrahedron

MedicineBenzo-β-carboline IsoneocryptolepineAlkaloid Series CryptolepinePharmacologyIndoloquinoline Isomer +4

Structure–activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues

Gitte Van Baelen, Steven Hostyn, Liene Dhooghe, +13

Bioorganic & Medicinal Chemistry

Structure–activity RelationshipBiochemistryAntiparasitic AgentMedicineCytotoxic Indoloquinoline Alkaloids +5

Synthesis and Antiplasmodial Activity of Aminoalkylamino-Substituted Neocryptolepine Derivatives

Ibrahim El Tantawy El Sayed, Pieter Van der Veken, Koen Steert, +11

Journal of Medicinal Chemistry

Microwave-assisted organic synthesis: scale-up of palladium-catalyzed aminations using single-mode and multi-mode microwave equipment

Kristof T. J. Loones, Bert U. W. Maes, Geert Rombouts, +2

Tetrahedron

Chemical EngineeringPalladium-catalyzed AminationsEngineeringMulti-mode Microwave EquipmentMicrowave-assisted Organic Synthesis +5

Synthesis of 7H-indolo[2,3-c]quinolines: study of the Pd-catalyzed intramolecular arylation of 3-(2-bromophenylamino)quinolines under microwave irradiation

Steven Hostyn, Bert U. W. Maes, Gitte Van Baelen, +3

Tetrahedron

Cross-coupling ReactionEngineeringOrganic ChemistryMicrowave IrradiationCatalysis +7

Pd-catalyzed intramolecular direct arylations at high temperature

Philippe Franck, Steven Hostyn, Beata Dajka‐Halasz, +4

Tetrahedron

Organometallic CatalysisCatalysisMolecular CatalysisChemistryHigh Temperature

Rapid palladium-catalyzed aminations of aryl chlorides with aliphatic amines under temperature-controlled microwave heating

Bert U. W. Maes, Kristof T. J. Loones, Steven Hostyn, +2

Tetrahedron

Chemical EngineeringAryl ChloridesEngineeringTemperature-controlled Microwave HeatingOrganic Chemistry +6

“Base Effect” in the Auto-Tandem Palladium-Catalyzed Synthesis of Amino-Substituted 1-Methyl-1<i>H</i>-α-carbolines

Ashok Kumar Yadav, Stefan Verbeeck, Steven Hostyn, +3

Organic Letters