Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies

Adriano Mollica, Roberto Costante, Atilla Akdemir, +5

Bioorganic & Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryBioorganic ChemistryBiochemistryDocking Studies +8

Design, Synthesis and Biological Evaluation of Two Opioid Agonist and Ca_v2.2 Blocker Multitarget Ligands

Adriano Mollica, Roberto Costante, Ettore Novellino, +8

Chemical Biology & Drug Design

N-type Voltage-dependent CaPain MedicineAnesthetic MechanismMolecular PainPharmacotherapy +18

Synthesis and anti-cancer activity of naturally occurring 2,5-diketopiperazines

Adriano Mollica, Roberto Costante, Serena Fiorito, +5

Fitoterapia

MedicineAnti-cancer ActivityOrganic ChemistryAnti-cancer AgentHeterocycle Chemistry +2

Novel Cyclic Biphalin Analogue with Improved Antinociceptive Properties

Adriano Mollica, Alfonso Carotenuto, Ettore Novellino, +12

ACS Medicinal Chemistry Letters

Pain MedicineMolecular PainProducts 9PharmacotherapyPharmaceutical Chemistry +17

Biological Active Analogues of the Opioid Peptide Biphalin: Mixed α/β³-Peptides

Adriano Mollica, Francesco Pinnen, Roberto Costante, +8

Journal of Medicinal Chemistry

Molecular PharmacologyBiochemistryMedicineBehavioral PharmacologyBiological Active Analogues +12

The Evolution of Peptide Synthesis: From Early Days to Small Molecular Machines

Adriano Mollica, Francesco Pinnen, Azzurra Stefanucci, +1

Current Bioactive Compounds

Bioorganic ChemistryEngineeringPeptide EngineeringMolecular BiologyPeptide Science +17

Analgesic Properties of Opioid/NK1 Multitarget Ligands with Distinct in Vitro Profiles in Naive and Chronic Constriction Injury Mice

Joanna Starnowska-Sokół, Roberto Costante, Karel Guillemyn, +13

ACS Chemical Neuroscience

Pain DisordersPain MedicineNeuropathic PainMolecular PainPharmacotherapy +20

Antinociceptive profile of potent opioid peptide AM94, a fluorinated analogue of biphalin with non‐hydrazine linker

Adriano Mollica, Roberto Costante, Azzurra Stefanucci, +4

Journal of Peptide Science

Arginine- and Lysine-rich Peptides: Synthesis, Characterization and Antimicrobial Activity

Adriano Mollica, Giorgia Macedonio, Azzurra Stefanucci, +11

Letters in Drug Design & Discovery

Structure-Activity Relationships of Biphalin Analogs and their Biological Evaluation on Opioid Receptors

Federica Feliciani, Francesco Pinnen, Azzurra Stefanucci, +4

Mini-Reviews in Medicinal Chemistry

Biphalin AnalogsPain MedicineMolecular PainPharmacotherapyExperimental Pharmacology +22