Francesca De Lorenzo

Evidence for an Additive Neurorestorative Effect of Simultaneously Administered CDNF and GDNF in Hemiparkinsonian Rats: Implications for Different Mechanism of Action

Merja H. Voutilainen, Francesca De Lorenzo, Polina Stepanova et al. · eNeuro · 2017 · 60 citations · Full text

Medicine, Neuroscience, Pharmacology +17

CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress

Francesca De Lorenzo, Patrick Lüningschrör, Jin Han Nam et al. · Brain · 2023 · 45 citations · Full text

Life Sciences, Neurology, Neuroscience +17

A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy

Tony Eteläinen, M. Catarina Silva, Johanna Uhari‐Väänänen et al. · Science Translational Medicine · 2023 · 33 citations

Life Sciences, Biochemistry, Neuroscience +17

5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein–Protein Interaction-Derived Functions

Henri T. Pätsi, Tommi Kilpeläinen, Mikael Jumppanen et al. · Journal of Medicinal Chemistry · 2024 · 12 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Removal of proteinase K resistant αSyn species does not correlate with cell survival in a virus vector-based Parkinson's disease mouse model

Tony Eteläinen, Tommi Kilpeläinen, Adele Ignatius et al. · Neuropharmacology · 2022 · 11 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17