Philipp M. Toth

Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment

Tim Schumann, Till Adhikary, Annika Wortmann et al. · Oncotarget · 2015 · 96 citations · Full text

Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion

Till Adhikary, Dominique T. Brandt, Kerstin Kaddatz et al. · Oncogene · 2012 · 86 citations · Full text

The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state

Till Adhikary, Annika Wortmann, Tim Schumann et al. · Nucleic Acids Research · 2015 · 79 citations · Full text

Inflammatory Lung Disease, Lung Inflammation, Immune Regulation +28

High-Affinity Peroxisome Proliferator-Activated Receptor β/δ-Specific Ligands with Pure Antagonistic or Inverse Agonistic Properties

Simone Naruhn, Philipp M. Toth, Till Adhikary et al. · Molecular Pharmacology · 2011 · 39 citations

Price for Opening the Transient Specificity Pocket in Human Aldose Reductase upon Ligand Binding: Structural, Thermodynamic, Kinetic, and Computational Analysis

C. Rechlin, Frithjof Scheer, Felix Terwesten et al. · ACS Chemical Biology · 2017 · 32 citations · Full text

Parent Ligand Scaffold, Engineering, Aldo-keto Reductase +25