Identification of a T follicular helper cell subset that drives anaphylactic IgE

Uthaman Gowthaman, Jennifer Chen, Biyan Zhang, +15

Science

Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages

Scott McComb, Erin Cessford, Norah A. Alturki, +6

Proceedings of the National Academy of Sciences

Divergent T follicular helper cell requirement for IgA and IgE production to peanut during allergic sensitization

Biyan Zhang, Elise Liu, Jake A. Gertie, +9

Science Immunology

IL-17 Silencing Does Not Protect Nonobese Diabetic Mice from Autoimmune Diabetes

Julie Joseph, Stefan Bittner, Fabian Kaiser, +2

The Journal of Immunology

Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium

Julie Joseph, Emmanuelle S. Ametepe, Naveen Haribabu, +4

Nature Communications

Clinical Isolates of <i>Pseudomonas aeruginosa</i> from Chronically Infected Cystic Fibrosis Patients Fail To Activate the Inflammasome during Both Stable Infection and Pulmonary Exacerbation

Kelsey E. Huus, Julie Joseph, Li Zhang, +4

The Journal of Immunology

Intrinsic Role of FoxO3a in the Development of CD8+ T Cell Memory

Fanny Tzelepis, Julie Joseph, Elias K. Haddad, +6

The Journal of Immunology

Lymphocyte DevelopmentAdaptive Immune SystemT-regulatory CellImmune RegulationImmunology +18

2022 White Paper on Recent Issues in Bioanalysis: Fda Draft Guidance on Immunogenicity Information in Prescription Drug Labeling, Lnp &amp; Viral Vectors Therapeutics/Vaccines Immunogenicity, Prolongation Effect, Ada Affinity, Risk-Based Approaches, Ngs, Qpcr, Ddpcr Assays ( <u>Part 3</u> – Recommendations on Gene Therapy, Cell Therapy, Vaccines Immunogenicity &amp; Technologies; Immunogenicity &amp; Risk Assessment of Biotherapeutics and Novel Modalities; NAb Assays Integrated Approach)

Luying Pan, Johanna Mora, Karl Walravens, +66

Bioanalysis

Preclinical TherapeuticsImmunohematologyCell TherapyEngineeringBiomolecular Tool +33

2022 White Paper on Recent Issues in Bioanalysis: ICH M10 BMV Guideline &amp; Global Harmonization; Hybrid Assays; Oligonucleotides &amp; ADC; Non-Liquid &amp; Rare Matrices; Regulatory Inputs ( <u>Part 1A</u> – Recommendations on Mass Spectrometry, Chromatography and Sample Preparation, Novel Technologies, Novel Modalities, and Novel Challenges, ICH M10 BMV Guideline &amp; Global Harmonization <u>Part 1B</u> - Regulatory Agencies' Inputs on Regulated Bioanalysis/BMV, Biomarkers/CDx/BAV, Immunogenicity, Gene &amp; Cell Therapy and Vaccine)

Matt Szapacs, Wenying Jian, Daniel S. Spellman, +83

Bioanalysis

2022 White Paper on Recent Issues in Bioanalysis: Enzyme Assay Validation, BAV for Primary End Points, Vaccine Functional Assays, Cytometry in Tissue, LBA in Rare Matrices, Complex NAb Assays, Spectral Cytometry, Endogenous Analytes, Extracellular Vesicles <u>Part 2</u> – Recommendations on Biomarkers/CDx, Flow Cytometry, Ligand-Binding Assays Development &amp; Validation; Emerging Technologies; Critical Reagents Deep Characterization

Giane Sumner, Steve Keller, James W. Huleatt, +71

Bioanalysis