Michiel M. Harmsen

Comparison of physical chemical properties of llama VHH antibody fragments and mouse monoclonal antibodies

Richard H.J van der Linden, Leon Frenken, Bernard de Geus et al. · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · 1999 · 450 citations

Immunocytochemical Technique, Allergy, Autoimmune Disease +11

Llama heavy-chain V regions consist of at least four distinct subfamilies revealing novel sequence features

Michiel M. Harmsen, Robin Ruuls, Isaäc J. Nijman et al. · Molecular Immunology · 2000 · 209 citations · Full text

Comparative Genomics, Genetics, Genomics +16

Early immunodiagnosis of fasciolosis in ruminants using recombinant Fasciola hepatica cathepsin L-like protease

J.B.W.J. Cornelissen, C.P.H. Gaasenbeek, F.H.M. Borgsteede et al. · International Journal for Parasitology · 2001 · 132 citations · Full text

Animal Physiology, Caprine, Autoimmune Disease +12

Selection and optimization of proteolytically stable llama single-domain antibody fragments for oral immunotherapy

Michiel M. Harmsen, C. B. van Solt, A. M. van Zijderveld-van Bemmel et al. · Applied Microbiology and Biotechnology · 2006 · 120 citations · Full text

Mucosal Vaccination, Allergy, Immunology +10

Overexpression of binding protein and disruption of the PMR1 gene synergistically stimulate secretion of bovine prochymosin but not plant Thaumatin in yeast

Michiel M. Harmsen, M. I. Bruyne, Harald Rau et al. · Applied Microbiology and Biotechnology · 1996 · 95 citations

Medicine, Genetics, Natural Sciences +9