Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells

Mitsutoshi Yamada, Bjarki Jóhannesson, Ido Sagi, +13

Nature

Regenerative MedicineType 1Adult Somatic NucleiInduced Pluripotent Stem CellDevelopmental Biology +9

Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome

Lisa C. Burnett, Charles A. LeDuc, Carlos R. Sulsona, +21

Journal of Clinical Investigation

Hyperphagia: Current concepts and future directions proceedings of the 2nd international conference on hyperphagia

Steven B. Heymsfield, Nicole M. Avena, Leslie J. Baier, +26

Obesity

Hypomorphism of Fto and Rpgrip1l causes obesity in mice

George Stratigopoulos, Lisa C. Burnett, Richard Rausch, +9

Journal of Clinical Investigation

ObesityMetabolic SyndromeEnergy HomeostasisInsulin SignalingDevelopmental Biology +12

Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production

Helen Chen, A. Kaitlyn Victor, Jonathon Klein, +18

JCI Insight

Protein SecretionMolecular RegulationPathologyMature Sg AbundancePrader-willi Syndrome +21

Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons

Liheng Wang, Yang Liu, George Stratigopoulos, +16

Journal of Clinical Investigation

Metabolic DisorderPrimary CiliumSynaptic SignalingInsulin SignalingSocial Sciences +20

Prader–Willi-Like Phenotype Caused by an Atypical 15q11.2 Microdeletion

Qiming Tan, Kathryn J. Potter, Lisa C. Burnett, +4

Genes

Determination of the half-life of circulating leptin in the mouse

Lisa C. Burnett, Adam Skowroński, Robert L. Rausch, +2

International Journal of Obesity

Animal PhysiologyKnockout MouseNeuropeptidesMedicineMammalian Physiology +6

Loss of the imprinted, non-coding Snord116 gene cluster in the interval deleted in the Prader Willi syndrome results in murine neuronal and endocrine pancreatic developmental phenotypes

Lisa C. Burnett, Gabriela Hubner, Charles A. LeDuc, +3

Human Molecular Genetics

Induced pluripotent stem cells (iPSC) created from skin fibroblasts of patients with Prader-Willi syndrome (PWS) retain the molecular signature of PWS

Lisa C. Burnett, Charles A. LeDuc, Carlos R. Sulsona, +8

Stem Cell Research

Epigenetic ChangeGeneticsMolecular GeneticsPws Large DeletionEpigenetics +21