Lena M. Brueckner

HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment

Till Milde, Marco Lodrini, Larissa Savelyeva et al. · Journal of Neuro-Oncology · 2012 · 129 citations

Hematological Malignancy, Tumor Biology, Chromatin +11

CDK4 inhibition restores G₁-S arrest in<i><i>MYCN</i>-</i>amplified neuroblastoma cells in the context of doxorubicin-induced DNA damage

Sina Gogolin, Volker Ehemann, Gabriele Becker et al. · Cell Cycle · 2013 · 63 citations · Full text

Cell Death, Cancer Biology, Neuroblastoma Cells +18

The FRA2C common fragile site maps to the borders of MYCN amplicons in neuroblastoma and is associated with gross chromosomal rearrangements in different cancers

Anne Blumrich, Marc Zapatka, Lena M. Brueckner et al. · Human Molecular Genetics · 2011 · 44 citations · Full text

Gross Chromosomal Rearrangements, Dna Breakage, Molecular Biology +16

Genomic rearrangements at the FRA2H common fragile site frequently involve non-homologous recombination events across LTR and L1(LINE) repeats

Lena M. Brueckner, Evgeny Sagulenko, Elisa M. Hess et al. · Human Genetics · 2012 · 15 citations

Non-homologous Recombination Events, Genome Instability, Genetics +8

Low p14ARF expression in neuroblastoma cells is associated with repressed histone mark status, and enforced expression induces growth arrest and apoptosis

Daniel Dreidax, Sina Gogolin, Christina I. Schroeder et al. · Human Molecular Genetics · 2013 · 13 citations

Cell Death, Pathology, Cancer Biology +16