Gary Shaw

Elraglusib (9-ING-41), a selective small-molecule inhibitor of glycogen synthase kinase-3 beta, reduces expression of immune checkpoint molecules PD-1, TIGIT and LAG-3 and enhances CD8+ T cell cytolytic killing of melanoma cells

Gary Shaw, Ludimila Cavalcante, Francis J. Giles et al. · Journal of Hematology & Oncology · 2022 · 43 citations · Full text

shRNA‐mediated PPARα knockdown in human glioma stem cells reduces <i>in vitro</i> proliferation and inhibits orthotopic xenograft tumour growth

Harry R. Haynes, Helen L. Scott, Clare Killick-Cole et al. · The Journal of Pathology · 2018 · 21 citations · Full text

Tumour Growth, Cancer Biology, Glioma +19

Hematopoietic stem cell gene therapy targeting TGFβ enhances the efficacy of irradiation therapy in a preclinical glioblastoma model

Tereza Andreou, Jennifer M. Williams, Rebecca J. Brownlie et al. · Journal for ImmunoTherapy of Cancer · 2021 · 17 citations · Full text

Cell Therapy, Immunology, Cell Replacement Therapy +25

Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection

Lynette P. Steele, Aarren J. Mannion, Gary Shaw et al. · iScience · 2021 · 13 citations · Full text

GSK-3 Inhibition Is Cytotoxic in Glioma Stem Cells through Centrosome Destabilization and Enhances the Effect of Radiotherapy in Orthotopic Models

Anke Brüning‐Richardson, Gary Shaw, Daniel Tams et al. · Cancers · 2021 · 12 citations · Full text