Alexander E. Chu

An all-atom protein generative model

Alexander E. Chu, Jinho Kim, Lucy Cheng et al. · Proceedings of the National Academy of Sciences · 2024 · 58 citations · Full text

De novo design of high-affinity protein binders with AlphaProteo

Vinícius Zambaldi, David La, Alexander E. Chu et al. · arXiv (Cornell University) · 2024 · 43 citations · Full text

Protein Assembly, Molecular Biology, Protein-binding Proteins +18

Interleukin-2 superkines by computational design

Junming Ren, Alexander E. Chu, Kevin M. Jude et al. · Proceedings of the National Academy of Sciences · 2022 · 31 citations · Full text

Optical control of fast and processive engineered myosins in vitro and in living cells

Paul V. Ruijgrok, Rajarshi P. Ghosh, Sasha Zemsky et al. · Nature Chemical Biology · 2021 · 26 citations · Full text

Living Cells, Engineering, Medicine +11

Soybean Cyst Nematode Resistance Emerged via Artificial Selection of Duplicated Serine Hydroxymethyltransferase Genes

Xiaoyi Wu, Guang‐Can Zhou, Yunxia Chen et al. · Frontiers in Plant Science · 2016 · 20 citations · Full text

Plant Genetics, Engineering, Plant Defense Gene +18