Siyuan Du

Conformational ensembles reveal the origins of serine protease catalysis

Siyuan Du, Rachael C. Kretsch, Jacob Parres-Gold et al. · Science · 2025 · 30 citations

Enzymology, Protein Assembly, Biochemistry +14

Evaluating the impact of X-ray damage on conformational heterogeneity in room-temperature (277 K) and cryo-cooled protein crystals

Filip Yabukarski, Tzanko Doukov, Daniel A. Mokhtari et al. · Acta Crystallographica Section D Structural Biology · 2022 · 22 citations · Full text

Refinement of multiconformer ensemble models from multi-temperature X-ray diffraction data

Siyuan Du, Stephanie A. Wankowicz, Filip Yabukarski et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 2023 · 18 citations · Full text

Materials Science, X-ray Crystallography, Engineering +9

Decoupling of catalysis and transition state analog binding from mutations throughout a phosphatase revealed by high-throughput enzymology

Craig J. Markin, Daniel A. Mokhtari, Siyuan Du et al. · Proceedings of the National Academy of Sciences · 2023 · 14 citations · Full text

Giant switchable ferroelectric photovoltage in double-perovskite epitaxial films through chemical negative strain

Jie Tu, Hangren Li, Xudong Liu et al. · Science Advances · 2025 · 10 citations · Full text