Emily A. Costa

Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers

Julien P. N. Papillon, Katsumasa Nakajima, Christopher D. Adair et al. · Journal of Medicinal Chemistry · 2018 · 225 citations · Full text

Brahma Homolog, Molecular Biology, Cancer Biology +19

Direct genome editing of patient-derived xenografts using CRISPR-Cas9 enables rapid in vivo functional genomics

Christopher H. Hulton, Emily A. Costa, Nisargbhai Shah et al. · Nature Cancer · 2020 · 50 citations · Full text

Direct Genome Editing, Xenotransplantation, Patient-derived Xenografts +13

Rlf–Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer

Metamia Ciampricotti, Triantafyllia Karakousi, Allison L. Richards et al. · PMC · 2021 · 43 citations · Full text

MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer

Rebecca Caeser, Christopher H. Hulton, Emily A. Costa et al. · iScience · 2021 · 37 citations · Full text

Systematically inferring I/O performance variability by examining repetitive job behavior

Emily A. Costa, Tirthak Patel, Benjamin Schwaller et al. · 2021 · 21 citations

Cluster Computing, Storage Performance, Engineering +29