Jan Madacki

Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression

Giulia Degiacomi, Andrej Benjak, Jan Madacki et al. · Scientific Reports · 2017 · 108 citations · Full text

A Common Mechanism of Inhibition of the Mycobacterium tuberculosis Mycolic Acid Biosynthetic Pathway by Isoxyl and Thiacetazone

Anna E. Grzegorzewicz, Jana Korduláková, Victoria Jones et al. · Journal of Biological Chemistry · 2012 · 99 citations · Full text

Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity

Paulo F. M. de Oliveira, Brigitte Guidetti, Alain Chamayou et al. · Molecules · 2017 · 86 citations · Full text

Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth

Aurélien Chollet, Giorgia Mori, Christophe Menendez et al. · European Journal of Medicinal Chemistry · 2015 · 52 citations · Full text

Mycobacterium Tuberculosis Growth, Pulmonary Tuberculosis, Medicine +11

New lipophilic isoniazid derivatives and their 1,3,4-oxadiazole analogues: Synthesis, antimycobacterial activity and investigation of their mechanism of action

Rudolf Vosátka, Martin Krátký, Markéta Švarcová et al. · European Journal of Medicinal Chemistry · 2018 · 48 citations

Medicinal Chemistry, Pharmaceutical Chemistry, Biochemistry +10