Matthew A. Brooke

Inflammatory Skin and Bowel Disease Linked to<i>ADAM17</i>Deletion

Diana C. Blaydon, Paolo Biancheri, Wei‐Li Di et al. · New England Journal of Medicine · 2011 · 304 citations · Full text

Chronic Inflammatory Diseases, Immunodeficiencies, Immunology +26

Correction: Corrigendum: ADAM17/EGFR axis promotes transglutaminase-dependent skin barrier formation through phospholipase C γ1 and protein kinase C pathways

Cristina Wolf, Yawen Qian, Matthew A. Brooke et al. · Scientific Reports · 2017 · 126 citations · Full text

Skin Development, Signal Transduction, Biochemistry +11

iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function

Matthew A. Brooke, Sarah Etheridge, Nihal Kaplan et al. · Human Molecular Genetics · 2014 · 80 citations · Full text

Cell Regulation, Molecular Regulation, Irhom2-dependent Regulation +15

Cryptogenic multifocal ulcerating stenosing enteritis associated with homozygous deletion mutations in cytosolic phospholipase A2-α

Matthew A. Brooke, Hilary Longhurst, Vincent Plagnol et al. · Gut · 2012 · 77 citations

Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17

Sathish Kumar Maney, David R. McIlwain, Robin Polz et al. · Science Signaling · 2015 · 59 citations · Full text