Matthew A. Brooke

Inflammatory Skin and Bowel Disease Linked to<i>ADAM17</i>Deletion

Diana C. Blaydon, Paolo Biancheri, Wei‐Li Di et al. · New England Journal of Medicine · 2011 · 310 citations · Full text

Medicine, Molecular Genetics, Pathology +17

Correction: Corrigendum: ADAM17/EGFR axis promotes transglutaminase-dependent skin barrier formation through phospholipase C γ1 and protein kinase C pathways

Cristina Wolf, Yawen Qian, Matthew A. Brooke et al. · Scientific Reports · 2017 · 126 citations · Full text

Medicine, Cell Biology, Dermatology +15

iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function

Matthew A. Brooke, Sarah Etheridge, Nihal Kaplan et al. · Human Molecular Genetics · 2014 · 84 citations · Full text

Life Sciences, Dermatology, Molecular Biology +13

Cryptogenic multifocal ulcerating stenosing enteritis associated with homozygous deletion mutations in cytosolic phospholipase A2-α

Matthew A. Brooke, Hilary Longhurst, Vincent Plagnol et al. · Gut · 2012 · 79 citations

Life Sciences, Genetics, Molecular Genetics +15

Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17

Sathish Kumar Maney, David R. McIlwain, Robin Polz et al. · Science Signaling · 2015 · 62 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10