Lydia Young

Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry–mass spectrometry

Lydia Young, Janet C. Saunders, Rachel Mahood et al. · Nature Chemistry · 2014 · 282 citations · Full text

Biochemistry, Natural Sciences, Medicine +11

Ion Mobility Spectrometry–Mass Spectrometry Defines the Oligomeric Intermediates in Amylin Amyloid Formation and the Mode of Action of Inhibitors

Lydia Young, Ping Cao, Daniel P. Raleigh et al. · Journal of the American Chemical Society · 2013 · 181 citations · Full text

Protein Assembly, Amylin Amyloid Formation, Oligomer Formation +19

An in vivo platform for identifying inhibitors of protein aggregation

Janet C. Saunders, Lydia Young, Rachel Mahood et al. · Nature Chemical Biology · 2015 · 85 citations · Full text

Molecular Docking, Drug Target, Biochemistry +11

De novo design of a biologically active amyloid

Rodrigo Gallardo, Meine Ramakers, Frederik De Smet et al. · Science · 2016 · 72 citations · Full text

Active Amyloid, Immunology, Neurochemical Biomarkers +16

Aggregating sequences that occur in many proteins constitute weak spots of bacterial proteostasis

Ladan Khodaparast, Laleh Khodaparast, Rodrigo Gallardo et al. · Nature Communications · 2018 · 71 citations · Full text